To assess the utilization of lenticules extricated utilizing small incision lenticule extraction (SMILE) surgery as a surgical alternative for wound closure in corneal perforation.

Corneal lenticules obtained through SMILE surgery with central thickness more than 100 micrometer were fixed over corneal perforation sites using 10-0 nylon interrupted stitches. Patients were monitored for a minimum of 3 months and were assessed using fluorescein,slit-lamp microscopy and best spectacle-corrected visual acuity (BSCVA) measurements. Postoperative complications throughout the study period were recorded.

Corneal perforations were successfully sealed in all 4 patients; 2 patients (50%) exhibited improved postoperative BCVA. Between 2 and 6 weeks after the operation, part of the lenticules became incorporated into the corneal stroma and complete reepithelialization was achieved. During the follow-up period of 3 months, no evidence of infection, relapse, or perforation was detected in any patient.

These starter discoveries recommend that the utilization of corneal lenticules might be a protected and viable careful option for corneal perforation closure, with potential clinical application as moderately basic and cheap transitory measures to improve the state of the cornea for further authoritative studies.